Spain captain Sergio Busquets has tested positive for Covid-19 five days before the start of Euro 2020.
The Spanish Football Federation (RFEF) confirmed on Sunday the Barcelona midfielder has left their Las Rozas training camp after posting a positive result in the latest round of testing.
However, the rest of the team all posted negative results two days after their 0-0 draw against Portugal in Madrid.
Spain take on Lithuania in Leganes on Tuesday in their last warm-up game before the European Championship, but they will now be forced to field players from their U21 side to follow strict health protocols.
Spain U21 boss Luis De La Fuente will also take charge of the team instead of the senior team’s head coach Luis Enrique, said a RFEF statement.